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Activated from the antibiotic rifampicin and a variety of plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to particular ligands is species-precise. Activated by Normally happening steroids, such as pregnenolone and progesterone. Binds to a reaction aspect during the promoters of your CYP3A4 and ABCB1/MDR1 ge